Artículos por temáticas

Antiviral therapy: Valacyclovir Treatment of Alzheimer's Disease (VALAD) Trial: protocol for a randomised, double-blind,placebo-controlled, treatment trial

Devanand DP, Andrews H, Kreisl WC, Razlighi Q, Gershon A, Stern Y, Mintz A, Wisniewski T, Acosta E, Pollina J, Katsikoumbas M, Bell KL, Pelton GH, Deliyannides D, Prasad KM, Huey ED.

BMJ Open. 2020 Feb 6;10(2):e032112. doi: 10.1136/bmjopen-2019-032112.

Efficacy and safety of MAO-B inhibitor versus donepezil in Chinese elderly stroke patients with Alzheimer disease: A potential therapeutic option

Yang H, Han W, Li H.

Pak J Pharm Sci. 2020 May;33(3(Special)):1349-1354.

Tau Protein Aggregation in Alzheimer's Disease: Recent Advances in the Development of Novel Therapeutic Agents

Monteiro KLC, Alcântara MGDS, de Aquino TM, da Silva-Júnior EF.

Curr Pharm Des. 2020;26(15):1682-1692. doi: 10.2174/1381612826666200414164038.

Transplantation of bone marrow mesenchymal stem cells improves cognitive deficits and alleviates neuropathology in animal models of Alzheimer's disease: a meta-analytic review on potential mechanisms

Qin C, Lu Y, Wang K, Bai L, Shi G, Huang Y, Li Y.

Transl Neurodegener. 2020 May 27;9(1):20. doi: 10.1186/s40035-020-00199-x.

Design and Rationale of the PACt-MD Randomized Clinical Trial: Prevention of Alzheimer's dementia with Cognitive remediation plus transcranial direct current stimulation in Mild cognitive impairment and Depression

Rajji TK, Bowie CR, Herrmann N, Pollock BG, Bikson M, Blumberger DM, Butters MA, Daskalakis ZJ, Fischer CE, Flint AJ, Golas AC, Graff-Guerrero A, Kumar S, Lourenco L, Mah L, Ovaysikia S, Thorpe KE, Vo

J Alzheimers Dis. 2020;76(2):733-751. doi: 10.3233/JAD-200141.

Evaluation of the efficacy of pimavanserin in the treatment of agitation and aggression in patients with Alzheimer's disease psychosis: A post hoc analysis

Ballard CG, Coate B, Abler V, Stankovic S, Foff E.

Int J Geriatr Psychiatry. 2020 Nov;35(11):1402-1408. doi: 10.1002/gps.5381. Epub 2020 Aug 25.

Computer-Aided Drug Design of β-Secretase, γ-Secretase and Anti-Tau Inhibitors for the Discovery of Novel Alzheimer's Therapeutics

Mouchlis VD, Melagraki G, Zacharia LC, Afantitis A.

Int J Mol Sci. 2020 Jan 21;21(3):703. doi: 10.3390/ijms21030703.

The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies

Albrahim T.

Neurosciences (Riyadh). 2020 Jan;25(1):4-17. doi: 10.17712/nsj.2020.1.20190037.

The cholinergic system in subtypes of Alzheimer's disease: an in vivo longitudinal MRI study

Machado A, Ferreira D, Grothe MJ, Eyjolfsdottir H, Almqvist PM, Cavallin L, Lind G, Linderoth B, Seiger Å, Teipel S, Wahlberg LU, Wahlund LO, Westman E, Eriksdotter M; Alzheimer’s Disease Neuroimaging

Alzheimers Res Ther. 2020 May 6;12(1):51. doi: 10.1186/s13195-020-00620-7.

US, EU, and Japanese Regulatory Guidelines for Development of Drugs for Treatment of Alzheimer's Disease: Implications for Global Drug Development

Morant AV, Vestergaard HT, Lassen AB, Navikas V.

Clin Transl Sci. 2020 Jul;13(4):652-664. doi: 10.1111/cts.12755. Epub 2020 Mar 3.

Evaluation of the effect of aroma oil as a bath salt on cognitive function

Kouzuki M, Kitao S, Kaju T, Urakami K.

Psychogeriatrics. 2020 Mar;20(2):163-171. doi: 10.1111/psyg.12481. Epub 2019 Oct 2.

Reactions to Multiple Ascending Doses of the Microtubule Stabilizer TPI-287 in Patients With Alzheimer Disease, Progressive Supranuclear Palsy, and Corticobasal Syndrome: A Randomized Clinical Trial

Tsai RM, Miller Z, Koestler M, Rojas JC, Ljubenkov PA, Rosen HJ, Rabinovici GD, Fagan AM, Cobigo Y, Brown JA, Jung JI, Hare E, Geldmacher DS, Natelson-Love M, McKinley EC, Luong PN, Chuu EL, Powers R,

JAMA Neurol. 2020 Feb 1;77(2):215-224. doi: 10.1001/jamaneurol.2019.3812.

Postmortem Analysis in a Clinical Trial of AAV2-NGF Gene Therapy for Alzheimer's Disease Identifies a Need for Improved Vector Delivery

Castle MJ, Baltanás FC, Kovacs I, Nagahara AH, Barba D, Tuszynski MH.

Hum Gene Ther. 2020 Apr;31(7-8):415-422. doi: 10.1089/hum.2019.367. Epub 2020 Mar 30.

[Mechanisms of electroacupuncture for improving Alzheimer's disease from reducing β amyloid protein level]

Yang WD, Dong WG.

Zhen Ci Yan Jiu. 2020 May 25;45(5):426-31. doi: 10.13702/j.1000-0607.180885.

Short and medium-term effects of a multicomponent physical exercise program with a Mediterranean diet on bone mineral density, gait, balance, and fall risk for patients with Alzheimer disease: Randomized controlled clinical trial study protocol

Puente-González AS, Sánchez-González F, Hernández-Xumet JE, Sánchez-Sánchez MC, Barbero-Iglesias FJ, Méndez-Sánchez R.

Medicine (Baltimore). 2020 Sep 18;99(38):e22385. doi: 10.1097/MD.0000000000022385.