Artículos por temáticas

Unveiling the mTOR pathway modulation by SGLT2 inhibitors: a novel approach to Alzheimer's disease in type 2 diabetes

Ramakrishan P, Rajangam J, Mahinoor SS, Bisht S, Mekala S, Upadhyay DK, Solomon VR, Sabarees G, Pelluri R.

Metab Brain Dis. 2025 Feb 26;40(3):132. doi: 10.1007/s11011-025-01555-4.

Effect of a single nonpharmacological intervention on cognitive functioning in older adults with mild-to-moderate Alzheimer's disease: A meta-analysis of randomized controlled trials

Chen K, Zhao X, Zhou J.

J Prev Alzheimers Dis. 2025 Mar;12(3):100050. doi: 10.1016/j.tjpad.2024.100050. Epub 2025 Jan 1.

The neuroprotective role of volatile oils: insights into chemical profiles, characteristics, neurochemical mechanisms, and preclinical studies in Alzheimer's disease

Suryawanshi M, Gujarathi P, Prajapati B, Vinchurkar K, Gujarathi P.

Inflammopharmacology. 2025 Feb;33(2):627-667. doi: 10.1007/s10787-024-01626-5. Epub 2025 Jan 22.

Innovations in noninvasive sensory stimulation treatments to combat Alzheimer's disease

Park JM, Tsai LH.

PLoS Biol. 2025 Feb 28;23(2):e3003046. doi: 10.1371/journal.pbio.3003046. eCollection 2025 Feb.

Sex-specific associations of neurodegeneration and inflammatory biomarkers with intrinsic capacity in older adults: Findings from the 4-year longitudinal Multidomain Alzheimer's Prevention Trial (MAPT)

de Assunção Cortez Corrêa LC, Raffin J, Vellas B, Guerra RO, de Souto Barreto P.

Maturitas. 2025 Feb;193:108191. doi: 10.1016/j.maturitas.2024.108191. Epub 2025 Jan 3.

Favorable long-term cognitive outcomes following recurrent ARIA linked to amyloid-lowering therapies: two cases

Zavarella M, Cecchetti G, Rugarli G, Ghirelli A, Bottale I, Orlandi F, Spinelli EG, Santangelo R, Caso F, Calloni SF, Vezzulli PQ, Falini A, Magnani G, Agosta F, Filippi M.

J Neurol. 2025 Jan 24;272(2):168. doi: 10.1007/s00415-025-12910-x.

Immune Modulation in Alzheimer's Disease: From Pathogenesis to Immunotherapy

Balkhi S, Di Spirito A, Poggi A, Mortara L.

Cells. 2025 Feb 12;14(4):264. doi: 10.3390/cells14040264.

Effect of donepezil on bone metabolism among older adults with Alzheimer's disease

North R, Liu AJ, Pieper C, Danus S, Thacker CR, Ashner M, Colón-Emeric C, Lee RH.

Contemp Clin Trials. 2025 Jan;148:107748. doi: 10.1016/j.cct.2024.107748. Epub 2024 Nov 19.

Protocol for an intergenerational randomized controlled trial to enhance physical activity in older adults at risk for Alzheimer's disease

Walker CS, Noriega de la Colina AE, Li L, Boulanger C, Thovinakere N, Noly-Gandon A, Barnoin G, Bennett M, Caplan J, Côté L, Elbaz S, Bao SFK, Kara R, Lavoie N, Nguyen M, Otaner F, Pallett-Wiesel H, P

J Prev Alzheimers Dis. 2025 Mar;12(3):100039. doi: 10.1016/j.tjpad.2024.100039. Epub 2025 Jan 9.

Insights Into the Therapeutic Potential of SIRT1-modifying Compounds for Alzheimer's Disease: A Focus on Molecular Mechanisms

AlHayani DA, Kubaev A, Uthirapathy S, Mandaliya V, Ballal S, Kalia R, Arya R, Gabble BC, Alasheqi MQ, Kadhim AJ.

J Mol Neurosci. 2025 Feb 25;75(1):29. doi: 10.1007/s12031-025-02324-9.

Mitochondrial dysfunction in Alzheimer's disease: a key frontier for future targeted therapies

Wang S, Liao Z, Zhang Q, Han X, Liu C, Wang J.

Front Immunol. 2025 Jan 14;15:1484373. doi: 10.3389/fimmu.2024.1484373. eCollection 2024.

Treatment of Alzheimer's Disease subjects with expanded non-genetically modified autologous natural killer cells (SNK01): a phase I study

Zúñiga CH, Acosta BI, Menchaca R, Amescua CA, Hong S, Hui L, Gil M, Rhee YH, Yoon S, Kim M, Chang PY, Kim YM, Song PY, Betito K.

Alzheimers Res Ther. 2025 Feb 12;17(1):40. doi: 10.1186/s13195-025-01681-2.

Comparative effectiveness of SGLT2 inhibitors and GLP-1 receptor agonists in preventing Alzheimer's disease, vascular dementia, and other dementia types among patients with type 2 diabetes

Sun M, Wang X, Lu Z, Yang Y, Lv S, Miao M, Chen WM, Wu SY, Zhang J.

Diabetes Metab. 2025 Mar;51(2):101623. doi: 10.1016/j.diabet.2025.101623. Epub 2025 Feb 12.

Bifidobacterium infantis and Bifidobacterium breve Improve Symptomatology and Neuronal Damage in Neurodegenerative Disease: A Systematic Review

Reiriz M, Beltrán-Velasco AI, Echeverry-Alzate V, Martínez-Miguel E, Gómez-Senent S, Uceda S, Clemente-Suárez VJ.

Nutrients. 2025 Jan 22;17(3):391. doi: 10.3390/nu17030391.

Efficacy And Safety of Dual Orexin Receptor Antagonist (DORA) For Sleep Disturbance in Patients With Alzheimer's Disease Dementia. A Review Article

Alshiban A, Hasoglu T, Oster J.

Am J Geriatr Psychiatry. 2025 Feb;33(2):209-218. doi: 10.1016/j.jagp.2024.09.016. Epub 2024 Oct 3.