Artículos por temáticas

An Expanded Narrative Review of Neurotransmitters on Alzheimer's Disease: The Role of Therapeutic Interventions on Neurotransmission

Akyuz E, Arulsamy A, Aslan FS, Sarisözen B, Guney B, Hekimoglu A, Yilmaz BN, Retinasamy T, Shaikh MF.

Mol Neurobiol. 2025 Feb;62(2):1631-1674. doi: 10.1007/s12035-024-04333-y. Epub 2024 Jul 16.

Unveiling tomorrow: Carbonic anhydrase activators and inhibitors pioneering new frontiers in Alzheimer's disease

Mishra KA, Sethi KK.

Arch Pharm (Weinheim). 2025 Jan;358(1):e2400748. doi: 10.1002/ardp.202400748. Epub 2024 Nov 6.

Exploring DPP IV inhibitors for Alzheimer's disease: Bridging diabetes and neurodegeneration

Pattanaik S, Prusty SK, Sahu PK.

Brain Res. 2025 Feb 1;1848:149342. doi: 10.1016/j.brainres.2024.149342. Epub 2024 Nov 19.

Fyn Kinase in Alzheimer's Disease: Unraveling Molecular Mechanisms and Therapeutic Implications

Meur S, Karati D.

Mol Neurobiol. 2025 Jan;62(1):643-660. doi: 10.1007/s12035-024-04286-2. Epub 2024 Jun 18.

Targeting tau in Alzheimer's and beyond: Insights into pathology and therapeutic strategies

Singh S, Khan S, Shahid M, Sardar M, Hassan MI, Islam A.

Ageing Res Rev. 2025 Feb;104:102639. doi: 10.1016/j.arr.2024.102639. Epub 2024 Dec 16.

The LDL Receptor-Related Protein 1: Mechanisms and roles in promoting Aβ efflux transporter in Alzheimer's disease

Li W, Chen C, Xu B, Chen J, Yang M, Gao L, Zhou J.

Biochem Pharmacol. 2025 Jan;231:116643. doi: 10.1016/j.bcp.2024.116643. Epub 2024 Nov 20.

TREM2 bridges microglia and extracellular microenvironment: Mechanistic landscape and therapeutical prospects on Alzheimer's disease

Zhao Y, Guo Q, Tian J, Liu W, Wang X.

Ageing Res Rev. 2025 Jan;103:102596. doi: 10.1016/j.arr.2024.102596. Epub 2024 Nov 27.

Ferroptosis in Cognitive Impairment Associated with Diabetes and Alzheimer's Disease: Mechanistic Insights and New Therapeutic Opportunities

Ma M, Jing G, Tian Y, Yin R, Zhang M.

Mol Neurobiol. 2025 Feb;62(2):2435-2449. doi: 10.1007/s12035-024-04417-9. Epub 2024 Aug 7.

The Role of Gut Microbiota in the Neuroprotective Effects of Selenium in Alzheimer's Disease

Skalny AV, Aschner M, Santamaria A, Filippini T, Gritsenko VA, Tizabi Y, Zhang F, Guo X, Rocha JBT, Tinkov AA.

Mol Neurobiol. 2025 Feb;62(2):1675-1692. doi: 10.1007/s12035-024-04343-w. Epub 2024 Jul 16.

Emerging Pharmacological Approaches for Psychosis and Agitation in Alzheimer's Disease

Imbimbo C, Cotta Ramusino M, Leone S, Mazzacane F, De Franco V, Gatti A, Perini G, Costa A.

CNS Drugs. 2025 Feb;39(2):143-160. doi: 10.1007/s40263-024-01133-9. Epub 2024 Dec 2.

Peptide-based inhibitors and nanoparticles: Emerging therapeutics for Alzheimer's disease

Mojarad-Jabali S, Roh KH.

Int J Pharm. 2025 Jan 25;669:125055. doi: 10.1016/j.ijpharm.2024.125055. Epub 2024 Dec 7.

Promising Natural Remedies for Alzheimer's Disease Therapy

Thawabteh AM, Ghanem AW, AbuMadi S, Thaher D, Jaghama W, Karaman D, Karaman R.

Molecules. 2025 Feb 17;30(4):922. doi: 10.3390/molecules30040922.

Phytomolecules as Alzheimer's therapeutics: A comprehensive review

Hussain MK, Ahmad M, Khatoon S, Khan MV, Azmi S, Arshad M, Ahamad S, Saquib M.

Eur J Med Chem. 2025 Apr 15;288:117401. doi: 10.1016/j.ejmech.2025.117401. Epub 2025 Feb 17.

Amyloid-Related Imaging Abnormalities (ARIA) in Clinical Trials of Gantenerumab in Early Alzheimer Disease

Salloway S, Wojtowicz J, Voyle N, Lane CA, Klein G, Lyons M, Rossomanno S, Mazzo F, Bullain S, Barkhof F, Bittner T, Schneider A, Grundman M, Aldea R, Boada M, Smith J, Doody R.

JAMA Neurol. 2025 Jan 1;82(1):19-29. doi: 10.1001/jamaneurol.2024.3937.

Drug repurposing for Alzheimer's disease and other neurodegenerative disorders

Cummings JL, Zhou Y, Van Stone A, Cammann D, Tonegawa-Kuji R, Fonseca J, Cheng F.

Nat Commun. 2025 Feb 19;16(1):1755. doi: 10.1038/s41467-025-56690-4.