Artículos por temáticas

The Rationale and Design of the Reducing Pathology in Alzheimer's Disease through Angiotensin TaRgeting (RADAR) Trial

Kehoe PG, Blair PS, Howden B, Thomas DL, Malone IB, Horwood J, Clement C, Selman LE, Baber H, Lane A, Coulthard E, Passmore AP, Fox NC, Wilkinson IB, Ben-Shlomo Y.

J Alzheimers Dis. 2018;61(2):803-814. doi: 10.3233/JAD-170101.

Tramadol ameliorates behavioural, biochemical, mitochondrial and histological alterations in ICV-STZ-induced sporadic dementia of Alzheimer's type in rats

Dhull DK, Kumar A.

Inflammopharmacology. 2018 Aug;26(4):925-938. doi: 10.1007/s10787-017-0431-3. Epub 2017 Dec 16.

Identification of disulfiram as a secretase-modulating compound with beneficial effects on Alzheimer's disease hallmarks

Reinhardt S, Stoye N, Luderer M, Kiefer F, Schmitt U, Lieb K, Endres K.

Sci Rep. 2018 Jan 22;8(1):1329. doi: 10.1038/s41598-018-19577-7.

Comparative study of the effects of phosphatidylcholine rich in DHA and EPA on Alzheimer's disease and the possible mechanisms in CHO-APP/PS1 cells and SAMP8 mice

Che H , Zhou M , Zhang T , Zhang L , Ding L , Yanagita T , Xu J , Xue C , Wang Y .

Food Funct. 2018 Jan 24;9(1):643-654. doi: 10.1039/c7fo01342f.

Pharmacodynamics of atabecestat (JNJ-54861911), an oral BACE1 inhibitor in patients with early Alzheimer's disease: randomized, double-blind, placebo-controlled study

Timmers M, Streffer JR, Russu A, Tominaga Y, Shimizu H, Shiraishi A, Tatikola K, Smekens P, Börjesson-Hanson A, Andreasen N, Matias-Guiu J, Baquero M, Boada M, Tesseur I, Tritsmans L, Van Nueten L, En

Alzheimers Res Ther. 2018 Aug 23;10(1):85. doi: 10.1186/s13195-018-0415-6.

The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): study protocol for a randomized controlled trial

Scherer RW, Drye L, Mintzer J, Lanctôt K, Rosenberg P, Herrmann N, Padala P, Brawman-Mintzer O, Burke W, Craft S, Lerner AJ, Levey A, Porsteinsson A, van Dyck CH; ADMET 2 Research Group.

Trials. 2018 Jan 18;19(1):46. doi: 10.1186/s13063-017-2406-5.

Transcranial magnetic stimulation intervention in Alzheimer's disease: a research proposal for a randomized controlled trial

Marron EM, Viejo-Sobera R, Quintana M, Redolar-Ripoll D, Rodríguez D, Garolera M.

BMC Res Notes. 2018 Sep 5;11(1):648. doi: 10.1186/s13104-018-3757-z.

Similar clinical improvement and maintenance after rTMS at 5 Hz using a simple vs. complex protocol in Alzheimer's disease

Alcalá-Lozano R, Morelos-Santana E, Cortés-Sotres JF, Garza-Villarreal EA, Sosa-Ortiz AL, González-Olvera JJ.

Brain Stimul. 2018 May-Jun;11(3):625-627. doi: 10.1016/j.brs.2017.12.011. Epub 2017 Dec 29.

Similar treatment outcomes with Ginkgo biloba extract EGb 761 and donepezil in Alzheimer's dementia in very old age: A retrospective observational study

Rapp M, Burkart M, Kohlmann T, Bohlken J.

Int J Clin Pharmacol Ther. 2018 Mar;56(3):130-133. doi: 10.5414/CP203103.

Detecting Treatment Group Differences in Alzheimer's Disease Clinical Trials: A Comparison of Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog) and the Clinical Dementia Rating - Sum of Boxes (CDR-SB)

Wessels AM, Dowsett SA, Sims JR.

J Prev Alzheimers Dis. 2018;5(1):15-20. doi: 10.14283/jpad.2018.2.

Antiepileptic Drug Use and the Risk of Stroke Among Community-Dwelling People With Alzheimer Disease: A Matched Cohort Study

Sarycheva T, Lavikainen P, Taipale H, Tiihonen J, Tanskanen A, Hartikainen S, Tolppanen AM.

J Am Heart Assoc. 2018 Sep 18;7(18):e009742. doi: 10.1161/JAHA.118.009742.

Data-driven identification of endophenotypes of Alzheimer's disease progression: implications for clinical trials and therapeutic interventions

Geifman N, Kennedy RE, Schneider LS, Buchan I, Brinton RD.

Alzheimers Res Ther. 2018 Jan 15;10(1):4. doi: 10.1186/s13195-017-0332-0.

Exercise-induced brain-derived neurotrophic factor expression: Therapeutic implications for Alzheimer's dementia

Wang R, Holsinger RMD.

Ageing Res Rev. 2018 Dec;48:109-121. doi: 10.1016/j.arr.2018.10.002. Epub 2018 Oct 13.

Methylphenidate for Apathy in Community-Dwelling Older Veterans With Mild Alzheimer's Disease: A Double-Blind, Randomized, Placebo-Controlled Trial

Padala PR, Padala KP, Lensing SY, Ramirez D, Monga V, Bopp MM, Roberson PK, Dennis RA, Petty F, Sullivan DH, Burke WJ.

Am J Psychiatry. 2018 Feb 1;175(2):159-168. doi: 10.1176/appi.ajp.2017.17030316. Epub 2017 Sep 15.

A comparative study of eicosapentaenoic acid enriched phosphatidylcholine and ethyl ester in improving cognitive deficiency in Alzheimer's disease model rats

Wen M , Ding L , Zhang L , Cong P , Zhang T , Xu J , Chang Y , Wang Y , Xue C .

Food Funct. 2018 Apr 25;9(4):2184-2192. doi: 10.1039/c7fo01815k.