Targeting the neuronal calcium sensor DREAM with small-molecules for Huntington's disease treatment.

Lopez-Hurtado A, Peraza DA, Cercos P, Lagartera L, Gonzalez P, Dopazo XM, Herranz R, Gonzalez T, Martin-Martinez M, Mellström B, Naranjo JR, Valenzuela C, Gutierrez-Rodriguez M.

Sci Rep. 2019 May 13;9(1):7260. doi: 10.1038/s41598-019-43677-7.

Intranasal Administration of Mesenchymal Stem Cells Ameliorates the Abnormal Dopamine Transmission System and Inflammatory Reaction in the R6/2 Mouse Model of Huntington Disease.

Yu-Taeger L, Stricker-Shaver J, Arnold K, Bambynek-Dziuk P, Novati A, Singer E, Lourhmati A, Fabian C, Magg J, Riess O, Schwab M, Stolzing A, Danielyan L, Nguyen HHP.

Cells. 2019 Jun 15;8(6). pii: E595. doi: 10.3390/cells8060595.

Erucic acid, a nutritional PPARδ-ligand may influence Huntington's disease pathogenesis.

Altinoz MA, Ozpinar A, Ozpinar A, Hacker E.

Metab Brain Dis. 2019 Oct 17. doi: 10.1007/s11011-019-00500-6. [Epub ahead of print] Review.

Huntington's disease patients display progressive deficits in hippocampal-dependent cognition during a task of spatial memory.

Harris KL, Armstrong M, Swain R, Erzinclioglu S, Das T, Burgess N, Barker RA, Mason SL.

Cortex. 2019 Oct;119:417-427. doi: 10.1016/j.cortex.2019.07.014. Epub 2019 Aug 13.

Bim contributes to the progression of Huntington's disease-associated phenotypes.

Roberts SL, Evans T, Yang Y, Fu Y, Button RW, Sipthorpe RJ, Cowan K, Valionyte E, Anichtchik O, Li H, Lu B, Luo S.

Hum Mol Genet. 2020 Jan 15;29(2):216-227. doi: 10.1093/hmg/ddz275.

Yeast-model-based study identified myosin- and calcium-dependent calmodulin signalling as a potential target for drug intervention in chorea-acanthocytosis.

Soczewka P, Kolakowski D, Smaczynska-de Rooij I, Rzepnikowska W, Ayscough KR, Kaminska J, Zoladek T.

Dis Model Mech. 2019 Jan 28;12(1). pii: dmm036830. doi: 10.1242/dmm.036830.

Huntington's disease in the United States: Variation by demographic and socioeconomic factors.

Bruzelius E, Scarpa J, Zhao Y, Basu S, Faghmous JH, Baum A.

Mov Disord. 2019 Mar 13. doi: 10.1002/mds.27653. [Epub ahead of print]

Speech in prodromal and symptomatic Huntington's disease as a model of measuring onset and progression in dominantly inherited neurodegenerative diseases.

Chan JCS, Stout JC, Vogel AP.

Neurosci Biobehav Rev. 2019 Dec;107:450-460. doi: 10.1016/j.neubiorev.2019.08.009. Epub 2019 Aug 13. Review.

Excitatory synapse impairment and mitochondrial dysfunction in Huntington's disease: heat shock factor 1 (HSF1) converging mechanisms.

Zarate N, Gomez-Pastor R.

Neural Regen Res. 2020 Jan;15(1):69-70. doi: 10.4103/1673-5374.264459. No abstract available.

Dysfunctional striatal dopamine signaling in Huntington's disease.

Koch ET, Raymond LA.

J Neurosci Res. 2019 Dec;97(12):1636-1654. doi: 10.1002/jnr.24495. Epub 2019 Jul 15. Review.

Widespread Increased Diffusivity Reveals Early Cortical Degeneration in Huntington Disease.

Sampedro F, Martínez-Horta S, Perez-Perez J, Horta-Barba A, Martin-Lahoz J, Alonso-Solís A, Corripio I, Gomez-Anson B, Kulisevsky J.

AJNR Am J Neuroradiol. 2019 Sep;40(9):1464-1468. doi: 10.3174/ajnr.A6168.

Chorea-ballism as a dominant clinical manifestation in heteroplasmic mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome with A3251G mutation in mitochondrial genome: a case report.

Lahiri D, Sawale VM, Banerjee S, Dubey S, Roy BK, Das SK.

J Med Case Rep. 2019 Mar 6;13(1):63. doi: 10.1186/s13256-018-1936-0.

Author response: Evaluating depression and suicidality in tetrabenazine users with Huntington disease.

Schultz JL, Killoran A, Nopoulos PC, Moser DJ, Kamholz JA.

Neurology. 2019 Feb 26;92(9):448. doi: 10.1212/WNL.0000000000007000. No abstract available.

Chorea.

Termsarasab P.

Continuum (Minneap Minn). 2019 Aug;25(4):1001-1035. doi: 10.1212/CON.0000000000000763.

Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy.

Carbo M, Brandi V, Pascarella G, Staid DS, Colotti G, Polticelli F, Ilari A, Morea V.

Int J Mol Med. 2019 Oct 15. doi: 10.3892/ijmm.2019.4373. [Epub ahead of print]