Cortical circuit alterations precede motor impairments in Huntington's disease mice.

Burgold J, Schulz-Trieglaff EK, Voelkl K, Gutiérrez-Ángel S, Bader JM, Hosp F, Mann M, Arzberger T, Klein R, Liebscher S, Dudanova I.

Sci Rep. 2019 Apr 29;9(1):6634. doi: 10.1038/s41598-019-43024-w.

Chorea-related mutations in PDE10A result in aberrant compartmentalization and functionality of the enzyme.

Tejeda GS, Whiteley EL, Deeb TZ, Bürli RW, Moss SJ, Sheridan E, Brandon NJ, Baillie GS.

Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):677-688. doi: 10.1073/pnas.1916398117. Epub 2019 Dec 23.

Treadmill exercise rescues mitochondrial function and motor behavior in the CAG(140) knock-in mouse model of Huntington's disease.

Caldwell CC, Petzinger GM, Jakowec MW, Cadenas E.

Chem Biol Interact. 2019 Nov 26;315:108907. doi: 10.1016/j.cbi.2019.108907. [Epub ahead of print]

Adult-onset Huntington disease: An update.

Urrutia NL.

Nursing. 2019 Jul;49(7):36-43. doi: 10.1097/01.NURSE.0000559914.46449.29.

Perseverative Behavior on Verbal Fluency Task in Patients with Huntington's Disease: a Retrospective Study on a Large Patient Sample.

De Lucia N, Peluso S, Roca A, De Michele G, Trojano L, Salvatore E.

Arch Clin Neuropsychol. 2019 Dec 8. pii: acz052. doi: 10.1093/arclin/acz052. [Epub ahead of print]

EFFICACY OF CHOLESTEROL NOSE-TO-BRAIN DELIVERY FOR BRAIN TARGETING IN HUNTINGTON'S DISEASE.

Passoni A, Favagrossa M, Colombo L, Bagnati R, Gobbi M, Diomede L, Birolini G, Di Paolo E, Valenza M, Cattaneo E, Salmona M.

ACS Chem Neurosci. 2019 Dec 20. doi: 10.1021/acschemneuro.9b00581. [Epub ahead of print]

Genetic deletion of S6k1 does not rescue the phenotypic deficits observed in the R6/2 mouse model of Huntington's disease.

Irvine EE, Katsouri L, Plattner F, Al-Qassab H, Al-Nackkash R, Bates GP, Withers DJ.

Sci Rep. 2019 Nov 6;9(1):16133. doi: 10.1038/s41598-019-52391-3.

Behavioral Symptoms in Premanifest Huntington Disease Correlate with Reduced Frontal CB(1)R Levels.

Ceccarini J, Ahmad R, Van de Vliet L, Casteels C, Vandenbulcke M, Vandenberghe W, Van Laere K.

J Nucl Med. 2019 Jan;60(1):115-121. doi: 10.2967/jnumed.118.210393. Epub 2018 Jun 22.

Antisense oligonucleotides might change the therapeutic landscape for Huntington's disease.

Paulsen JS, Coffey CS.

Lancet Neurol. 2019 Oct;18(10):911-912. doi: 10.1016/S1474-4422(19)30329-1. No abstract available.

Protective Effects of Antioxidants in Huntington's Disease: an Extensive Review.

Essa MM, Moghadas M, Ba-Omar T, Walid Qoronfleh M, Guillemin GJ, Manivasagam T, Justin-Thenmozhi A, Ray B, Bhat A, Chidambaram SB, Fernandes AJ, Song BJ, Akbar M.

Neurotox Res. 2019 Apr;35(3):739-774. doi: 10.1007/s12640-018-9989-9. Epub 2019 Jan 11. Review.

Psychosis and longitudinal outcomes in Huntington disease: the COHORT Study.

Connors MH, Teixeira-Pinto A, Loy CT.

J Neurol Neurosurg Psychiatry. 2019 Oct 13. pii: jnnp-2019-320646. doi: 10.1136/jnnp-2019-320646. [Epub ahead of print]

Activity Behaviour of Minipigs Transgenic for the Huntington Gene.

Rieke L, Fels M, Schubert R, Habbel B, Matheis T, Schuldenzucker V, Kemper N, Reilmann R.

J Huntingtons Dis. 2019 Jan 24. doi: 10.3233/JHD-180325. [Epub ahead of print]

Gedunin Degrades Aggregates of Mutant Huntingtin Protein and Intranuclear Inclusions via the Proteasomal Pathway in Neurons and Fibroblasts from Patients with Huntington's Disease.

Yang W, Xie J, Qiang Q, Li L, Lin X, Ren Y, Ren W, Liu Q, Zhou G, Wei W, Saiyin H, Ma L.

Neurosci Bull. 2019 Dec;35(6):1024-1034. doi: 10.1007/s12264-019-00421-5. Epub 2019 Aug 20.

A case-note review of continued pregnancies found to be at a high risk of Huntington's disease: considerations for clinical practice.

Wadrup F, Holden S, MacLeod R, Miedzybrodzka Z, Németh AH, Owens S, Pasalodos S, Quarrell O, Clarke AJ; UK Huntington’s Disease Predictive Testing Consortium..

Eur J Hum Genet. 2019 Mar 19. doi: 10.1038/s41431-019-0375-8. [Epub ahead of print]

Enhanced striatopallidal gamma-aminobutyric acid (GABA)(A) receptor transmission in mouse models of huntington's disease.

Perez-Rosello T, Gelman S, Tombaugh G, Cachope R, Beaumont V, Surmeier DJ.

Mov Disord. 2019 May;34(5):684-696. doi: 10.1002/mds.27622. Epub 2019 Feb 6.