Artículos por temáticas

Peptide-based inhibitors and nanoparticles: Emerging therapeutics for Alzheimer's disease

Mojarad-Jabali S, Roh KH.

Int J Pharm. 2025 Jan 25;669:125055. doi: 10.1016/j.ijpharm.2024.125055. Epub 2024 Dec 7.

Emerging Pharmacological Approaches for Psychosis and Agitation in Alzheimer's Disease

Imbimbo C, Cotta Ramusino M, Leone S, Mazzacane F, De Franco V, Gatti A, Perini G, Costa A.

CNS Drugs. 2025 Feb;39(2):143-160. doi: 10.1007/s40263-024-01133-9. Epub 2024 Dec 2.

Impact of Mouthwash-Induced Oral Microbiome Disruption on Alzheimer's Disease Risk: A Perspective Review

Boulares A, Jdidi H, Bragazzi NL.

Int Dent J. 2025 Feb;75(1):45-50. doi: 10.1016/j.identj.2024.07.005. Epub 2024 Oct 8.

Alzheimer Disease Anti-Amyloid Immunotherapies: Imaging Recommendations and Practice Considerations for Monitoring of Amyloid-Related Imaging Abnormalities

Cogswell PM, Andrews TJ, Barakos JA, Barkhof F, Bash S, Benayoun MD, Chiang GC, Franceschi AM, Jack CR Jr, Pillai JJ, Poussaint TY, Raji CA, Ramanan VK, Tanabe J, Tanenbaum L, Whitlow CT, Yu FF, Zahar

AJNR Am J Neuroradiol. 2025 Jan 8;46(1):24-32. doi: 10.3174/ajnr.A8469.

Deferiprone in Alzheimer Disease: A Randomized Clinical Trial

Ayton S, Barton D, Brew B, Brodtmann A, Clarnette R, Desmond P, Devos D, Ellis KA, Fazlollahi A, Fradette C, Goh AMY, Kalinowski P, Kyndt C, Lai R, Lim YY, Maruff P, O'Brien TJ, Rowe C, Salvado O, Sch

JAMA Neurol. 2025 Jan 1;82(1):11-18. doi: 10.1001/jamaneurol.2024.3733.

Use of lecanemab and donanemab in the Canadian healthcare system: Evidence, challenges, and areas for future research

Smith EE, Phillips NA, Feldman HH, Borrie M, Ganesh A, Henri-Bhargava A, Desmarais P, Frank A, Badhwar A, Barlow L, Bartha R, Best S, Bethell J, Bhangu J, Black SE, Bocti C, Bronskill SE, Burhan AM, C

J Prev Alzheimers Dis. 2025 Mar;12(3):100068. doi: 10.1016/j.tjpad.2025.100068. Epub 2025 Jan 31.

Inflammatory signaling pathways in Alzheimer's disease: Mechanistic insights and possible therapeutic interventions

Almutary AG, Begum MY, Kyada AK, Gupta S, Jyothi SR, Chaudhary K, Sharma S, Sinha A, Abomughaid MM, Imran M, Lakhanpal S, Babalghith AO, Abu-Seer EA, Avinash D, Alzahrani HA, Alhindi AA, Iqbal D, Kuma

Ageing Res Rev. 2025 Feb;104:102548. doi: 10.1016/j.arr.2024.102548. Epub 2024 Oct 16.

The Missing Link in Antiamyloid Therapy

Mandal PK, Maroon JC, Guha Roy R, Patira R, Gogniat MA, Sindhu B.

ACS Chem Neurosci. 2025 Feb 5;16(3):276-280. doi: 10.1021/acschemneuro.4c00825. Epub 2025 Jan 14.

Drug repurposing for Alzheimer's disease and other neurodegenerative disorders

Cummings JL, Zhou Y, Van Stone A, Cammann D, Tonegawa-Kuji R, Fonseca J, Cheng F.

Nat Commun. 2025 Feb 19;16(1):1755. doi: 10.1038/s41467-025-56690-4.

A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests

Warmenhoven N, Salvadó G, Janelidze S, Mattsson-Carlgren N, Bali D, Orduña Dolado A, Kolb H, Triana-Baltzer G, Barthélemy NR, Schindler SE, Aschenbrenner AJ, Raji CA, Benzinger TLS, Morris JC, Ibanez

Brain. 2025 Feb 3;148(2):416-431. doi: 10.1093/brain/awae346.

Phytomolecules as Alzheimer's therapeutics: A comprehensive review

Hussain MK, Ahmad M, Khatoon S, Khan MV, Azmi S, Arshad M, Ahamad S, Saquib M.

Eur J Med Chem. 2025 Apr 15;288:117401. doi: 10.1016/j.ejmech.2025.117401. Epub 2025 Feb 17.

Causal association between insulin sensitivity index and Alzheimer's disease

Xu F, Wu S, Gao S, Li X, Huang C, Chen Y, Zhu P, Liu G.

J Neurochem. 2025 Feb;169(2):e16254. doi: 10.1111/jnc.16254. Epub 2024 Oct 31.

Blood biomarkers in Down syndrome: Facilitating Alzheimer's disease detection and monitoring

Petersen ME, Flores-Aguilar L, Head E, Montoliu-Gaya L, Strydom A, Pape SE, Fortea J, Ashton NJ, Udeh-Momoh C, O'Bryant SE, German D, Despa F, Mapstone M, Zetterberg H.

Alzheimers Dement. 2025 Jan;21(1):e14364. doi: 10.1002/alz.14364. Epub 2024 Nov 13.

Drug delivery strategies with lipid-based nanoparticles for Alzheimer's disease treatment

Jang YJ, Kang SJ, Park HS, Lee DH, Kim JH, Kim JE, Kim DI, Chung CH, Yoon JK, Bhang SH.

J Nanobiotechnology. 2025 Feb 10;23(1):99. doi: 10.1186/s12951-025-03109-3.

The Potential Mechanism and the Role of Antioxidants in Mitigating Oxidative Stress in Alzheimer's Disease

Naik RA, Mir MN, Malik IA, Bhardwaj R, Alshabrmi FM, Mahmoud MA, Alhomrani M, Alamri AS, Alsanie WF, Hjazi A, Ghatak T, Poeggeler B, Singh MP, Ts G, Singh SK.

Front Biosci (Landmark Ed). 2025 Feb 18;30(2):25551. doi: 10.31083/FBL25551.