Artículos por temáticas

Lemborexant: First Approval

Scott LJ.

Drugs. 2020 Mar;80(4):425-432. doi: 10.1007/s40265-020-01276-1.

Type 3 diabetes (Alzheimer's disease): new insight for promising therapeutic avenues

Candasamy M, Mohamed Elhassan SA, Kumar Bhattamisra S, Hua WY, Sern LM, Binti Busthamin NA, Mohamad Ilni NB, Shun NS, Baohong L, Ya NS, Ying NW.

Panminerva Med. 2020 Sep;62(3):155-163. doi: 10.23736/S0031-0808.20.03879-3. Epub 2020 Mar 23.

Contribution of the Presenilins in the cell biology, structure and function of γ-secretase

Escamilla-Ayala A, Wouters R, Sannerud R, Annaert W.

Semin Cell Dev Biol. 2020 Sep;105:12-26. doi: 10.1016/j.semcdb.2020.02.005. Epub 2020 Mar 4.

Revisiting the Amyloid Cascade Hypothesis: From Anti-Aβ Therapeutics to Auspicious New Ways for Alzheimer's Disease

Uddin MS, Kabir MT, Rahman MS, Behl T, Jeandet P, Ashraf GM, Najda A, Bin-Jumah MN, El-Seedi HR, Abdel-Daim MM.

Int J Mol Sci. 2020 Aug 14;21(16):5858. doi: 10.3390/ijms21165858.

Takotsubo Cardiomyopathy in an Alzheimer Disease Patient: The Potential Contribution of Antidepressant Agents

Moulin Mares SRA, Groner JS, de Oliveira MP, Lírio LV, Coutinho PC, Luchi WM.

Alzheimer Dis Assoc Disord. 2020 Oct-Dec;34(4):360-361. doi: 10.1097/WAD.0000000000000395.

Agitation, Oxidative Stress, and Cytokines in Alzheimer Disease: Biomarker Analyses From a Clinical Trial With Nabilone for Agitation

Ruthirakuhan M, Herrmann N, Andreazza AC, Verhoeff NPLG, Gallagher D, Black SE, Kiss A, Lanctôt KL.

J Geriatr Psychiatry Neurol. 2020 Jul;33(4):175-184. doi: 10.1177/0891988719874118. Epub 2019 Sep 23.

White Matter and Neuroprotection in Alzheimer's Dementia

Lorenzini L, Fernandez M, Baldassarro VA, Bighinati A, Giuliani A, Calzà L, Giardino L.

Molecules. 2020 Jan 23;25(3):503. doi: 10.3390/molecules25030503.

Cyclic Nucleotides Signaling and Phosphodiesterase Inhibition: Defying Alzheimer's Disease

Sharma VK, Singh TG, Singh S.

Curr Drug Targets. 2020;21(13):1371-1384. doi: 10.2174/1389450121666200727104728.

Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer's Disease

Garcia-Leon JA, Caceres-Palomo L, Sanchez-Mejias E, Mejias-Ortega M, Nuñez-Diaz C, Fernandez-Valenzuela JJ, Sanchez-Varo R, Davila JC, Vitorica J, Gutierrez A.

Int J Mol Sci. 2020 Sep 18;21(18):6867. doi: 10.3390/ijms21186867.

Recent advances in tau-directed immunotherapy against Alzheimer's disease: an overview of pre-clinical and clinical development

Ng PY, Chang IS, Koh RY, Chye SM.

Metab Brain Dis. 2020 Oct;35(7):1049-1066. doi: 10.1007/s11011-020-00591-6. Epub 2020 Jul 6.

Protocol for an embedded pragmatic clinical trial to test the effectiveness of Aliviado Dementia Care in improving quality of life for persons living with dementia and their informal caregivers

Bristol AA, Convery KA, Sotelo V, Schneider CE, Lin SY, Fletcher J, Rupper R, Galvin JE, Brody AA.

Contemp Clin Trials. 2020 Jun;93:106005. doi: 10.1016/j.cct.2020.106005. Epub 2020 Apr 19.

Insights from Drosophila melanogaster model of Alzheimer's disease

Tue NT, Dat TQ, Ly LL, Anh VD, Yoshida H.

Front Biosci (Landmark Ed). 2020 Jan 1;25(1):134-146. doi: 10.2741/4798.

Butyrylcholinesterase: A Multifaceted Pharmacological Target and Tool

Ha ZY, Mathew S, Yeong KY.

Curr Protein Pept Sci. 2020;21(1):99-109. doi: 10.2174/1389203720666191107094949.

Unique Role of Caffeine Compared to Other Methylxanthines (Theobromine, Theophylline, Pentoxifylline, Propentofylline) in Regulation of AD Relevant Genes in Neuroblastoma SH-SY5Y Wild Type Cells

Janitschke D, Lauer AA, Bachmann CM, Seyfried M, Grimm HS, Hartmann T, Grimm MOW.

Int J Mol Sci. 2020 Nov 27;21(23):9015. doi: 10.3390/ijms21239015.

Pharmacological Activity and Mechanism of Tanshinone IIA in Related Diseases

Guo R, Li L, Su J, Li S, Duncan SE, Liu Z, Fan G.

Drug Des Devel Ther. 2020 Nov 5;14:4735-4748. doi: 10.2147/DDDT.S266911. eCollection 2020.