Next move in movement disorders (NEMO): developing a computer-aided classification tool for hyperkinetic movement disorders

van der Stouwe AMM, Tuitert I, Giotis I, Calon J, Gannamani R, Dalenberg JR, van der Veen S, Klamer MR, Telea AC, Tijssen MAJ.

BMJ Open. 2021 Oct 11;11(10):e055068. doi: 10.1136/bmjopen-2021-055068.

Efficacy and Safety of Fixed-Dose Deutetrabenazine in Children and Adolescents for Tics Associated With Tourette Syndrome: A Randomized Clinical Trial

Coffey B, Jankovic J, Claassen DO, Jimenez-Shahed J, Gertz BJ, Garofalo EA, Stamler DA, Wieman M, Savola JM, Gordon MF, Alexander JK, Barkay H, Harary E.

JAMA Netw Open. 2021 Oct 1;4(10):e2129397. doi: 10.1001/jamanetworkopen.2021.29397.

Fluc-EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease

Blumenstock S, Schulz-Trieglaff EK, Voelkl K, Bolender AL, Lapios P, Lindner J, Hipp MS, Hartl FU, Klein R, Dudanova I.

EMBO J. 2021 Oct 1;40(19):e107260. doi: 10.15252/embj.2020107260. Epub 2021 Aug 19.

Label-free photothermal disruption of cytotoxic aggregates rescues pathology in a C. elegans model of Huntington's disease

Nedosekin DA, Chen T, Ayyadevara S, Zharov VP, Shmookler Reis RJ.

Sci Rep. 2021 Oct 5;11(1):19732. doi: 10.1038/s41598-021-98661-x.

Evaluation of Executive Functions in Children with Rheumatic Heart Diseases

Aliyeva N, Yozgat Y, Bakhshaliyev N, Afshord TZ, Yozgat CY, Kilicoglu AG.

Pediatr Int. 2021 Oct 21. doi: 10.1111/ped.15035. Online ahead of print.

Rescue of BDNF expression by the thalamic parafascicular nucleus with chronic treatment with the mGluR2/3 agonist LY379268 may contribute to the LY379268 rescue of enkephalinergic striatal projection neurons in R6/2 Huntington's disease mice

Wang H, Del Mar N, Deng Y, Reiner A.

Neurosci Lett. 2021 Oct 15;763:136180. doi: 10.1016/j.neulet.2021.136180. Epub 2021 Aug 17.

Mitochondrial membranes modify mutant huntingtin aggregation

Adegbuyiro A, Sedighi F, Jain P, Pinti MV, Siriwardhana C, Hollander JM, Legleiter J.

Biochim Biophys Acta Biomembr. 2021 Oct 1;1863(10):183663. doi: 10.1016/j.bbamem.2021.183663. Epub 2021 Jun 2.

Safety and Efficacy of Flexible-Dose Deutetrabenazine in Children and Adolescents With Tourette Syndrome: A Randomized Clinical Trial

Jankovic J, Coffey B, Claassen DO, Jimenez-Shahed J, Gertz BJ, Garofalo EA, Stamler DA, Wieman M, Savola JM, Gordon MF, Alexander J, Barkay H, Harary E.

JAMA Netw Open. 2021 Oct 1;4(10):e2128204. doi: 10.1001/jamanetworkopen.2021.28204.

Quantifying the Onset of Unintended Weight Loss in Huntington's Disease: A Retrospective Analysis of Enroll-HD

Ogilvie AC, Nopoulos PC, Schultz JL.

J Huntingtons Dis. 2021 Oct 4. doi: 10.3233/JHD-210488. Online ahead of print.

Macromolecular crowding in solution alters huntingtin interaction and aggregation at interfaces

Groover SE, Adegbuyiro A, Fan CK, Hodges BL, Beasley M, Taylor K, Stonebraker AR, Siriwardhana C, Legleiter J.

Colloids Surf B Biointerfaces. 2021 Oct;206:111969. doi: 10.1016/j.colsurfb.2021.111969. Epub 2021 Jul 7.

Site of Cholesterol Oxidation Impacts Its Localization and Domain Formation in the Neuronal Plasma Membrane

Wilson KA, Wang L, O'Mara ML.

ACS Chem Neurosci. 2021 Oct 20;12(20):3873-3884. doi: 10.1021/acschemneuro.1c00395. Epub 2021 Oct 11.

Longitudinal preclinical evaluation of the novel radioligand [11C]CHDI-626 for PET imaging of mutant huntingtin aggregates in Huntington's disease

Bertoglio D, Verhaeghe J, Miranda A, Wyffels L, Stroobants S, Mrzljak L, Khetarpal V, Skinbjerg M, Liu L, Dominguez C, Munoz-Sanjuan I, Bard J, Staelens S.

Eur J Nucl Med Mol Imaging. 2021 Oct 15. doi: 10.1007/s00259-021-05578-8. Online ahead of print.

Targeting Mitochondrial Network Disorganization is Protective in C. elegans Models of Huntington's Disease

Machiela E, Rudich PD, Traa A, Anglas U, Soo SK, Senchuk MM, Van Raamsdonk JM.

Aging Dis. 2021 Oct 1;12(7):1753-1772. doi: 10.14336/AD.2021.0404. eCollection 2021 Oct.

Incidence of acute rheumatic fever in northern and western Uganda: a prospective, population-based study

Okello E, Ndagire E, Muhamed B, Sarnacki R, Murali M, Pulle J, Atala J, Bowen AC, DiFazio MP, Nakitto MG, Harik NS, Kansiime R, Longenecker CT, Lwabi P, Agaba C, Norton SA, Omara IO, Oyella LM, Parks

Lancet Glob Health. 2021 Oct;9(10):e1423-e1430. doi: 10.1016/S2214-109X(21)00288-6. Epub 2021 Aug 19.

Age-related mitochondrial alterations in brain and skeletal muscle of the YAC128 model of Huntington disease

Bečanović K, Muhammad A, Gadawska I, Sachdeva S, Walker D, Lazarowski ER, Franciosi S, Park KHJ, Côté HCF, Leavitt BR.

NPJ Aging Mech Dis. 2021 Oct 14;7(1):26. doi: 10.1038/s41514-021-00079-2.