New developments in Huntington's disease and other triplet repeat diseases: DNA repair turns to the dark side

Lahue RS.

Neuronal Signal. 2020 Nov 16;4(4):NS20200010. doi: 10.1042/NS20200010. eCollection 2020 Dec.

Molecular Mechanisms Underlying Muscle Wasting in Huntington's Disease

Bozzi M, Sciandra F.

Int J Mol Sci. 2020 Nov 5;21(21):8314. doi: 10.3390/ijms21218314.

THE PHARMACOLOGICAL CASE FOR CANNABIGEROL (CBG)

Nachnani R, Raup-Konsavage WM, Vrana KE.

J Pharmacol Exp Ther. 2020 Nov 9:JPET-MR-2020-000340. doi: 10.1124/jpet.120.000340. Online ahead of print.

Expanding the arsenal against Huntington's disease- Herbal drugs and their nanoformulations

Vishwas S, Gulati M, Kapoor B, Gupta S, Singh SK, Awasthi A, Khan A, Goyal A, Bansal A, Baishnab S, Singh TG, Arora S, Porwal O, Kumar A, Kumar V.

Curr Neuropharmacol. 2020 Nov 8. doi: 10.2174/1570159X18666201109090824. Online ahead of print.

Inflammation in Huntington's disease: A few new twists on an old tale

Valadão PAC, Santos KBS, Ferreira E Vieira TH, Macedo E Cordeiro T, Teixeira AL, Guatimosim C, de Miranda AS.

J Neuroimmunol. 2020 Nov 15;348:577380. doi: 10.1016/j.jneuroim.2020.577380. Epub 2020 Aug 31.

Cholesteryl ester levels are elevated in the caudate and putamen of Huntington's disease patients

Phillips GR, Hancock SE, Brown SHJ, Jenner AM, Kreilaus F, Newell KA, Mitchell TW.

Sci Rep. 2020 Nov 20;10(1):20314. doi: 10.1038/s41598-020-76973-8.

Risk-Taking Behaviors in Huntington's Disease

McDonell K, Ciriegio AE, Pfalzer AC, Hale L, Shiino S, Riordan H, Moroz S, Darby R, Compas BE, Claassen DO.

J Huntingtons Dis. 2020 Nov 6. doi: 10.3233/JHD-200431. Online ahead of print.

Glucose, glycolysis, and neurodegenerative diseases

Tang BL.

J Cell Physiol. 2020 Nov;235(11):7653-7662. doi: 10.1002/jcp.29682. Epub 2020 Apr 2.

The Accumulation of Tau in Postsynaptic Structures: A Common Feature in Multiple Neurodegenerative Diseases?

Teravskis PJ, Ashe KH, Liao D.

Neuroscientist. 2020 Oct-Dec;26(5-6):503-520. doi: 10.1177/1073858420916696. Epub 2020 May 9.

Hemichorea as Presentation of Acute Cortical Ischemic Stroke. Case Series and Review of the Literature

Carbayo Á, Sarto J, Santana D, Compta Y, Urra X.

J Stroke Cerebrovasc Dis. 2020 Oct;29(10):105150. doi: 10.1016/j.jstrokecerebrovasdis.2020.105150. Epub 2020 Jul 27.

RUES2 hESCs exhibit MGE-biased neuronal differentiation and muHTT-dependent defective specification hinting at SP1

Conforti P, Besusso D, Brocchetti S, Campus I, Cappadona C, Galimberti M, Laporta A, Iennaco R, Rossi RL, Dickinson VB, Cattaneo E.

Neurobiol Dis. 2020 Oct 13:105140. doi: 10.1016/j.nbd.2020.105140. Online ahead of print.

Bacteria metabolites from Peganum harmala L. polysaccharides inhibits polyQ aggregation through proteasome-mediated protein degradation in C. elegans

Guo X, Yuan J, Song X, Wang X, Sun Q, Tian J, Li X, Ding M, Liu Y.

Int J Biol Macromol. 2020 Oct 15;161:681-691. doi: 10.1016/j.ijbiomac.2020.06.091. Epub 2020 Jun 13.

Structural Model of the Proline-Rich Domain of Huntingtin Exon-1 Fibrils

Falk AS, Bravo-Arredondo JM, Varkey J, Pacheco S, Langen R, Siemer AB.

Biophys J. 2020 Nov 17;119(10):2019-2028. doi: 10.1016/j.bpj.2020.10.010. Epub 2020 Oct 20.

Complex Movement Disorders in Ataxia with Oculomotor Apraxia Type 1: Beyond the Cerebellar Syndrome

Pedroso JL, Vale TC, da Costa SCG, Santos M, Alonso I, Barsottini OGP.

Tremor Other Hyperkinet Mov (N Y). 2020 Oct 7;10:39. doi: 10.5334/tohm.557.

The Discovery of Highly Potent THP Derivatives as OCTN2 Inhibitors: From Structure-Based Virtual Screening to In Vivo Biological Activity

Di Cristo F, Calarco A, Digilio FA, Sinicropi MS, Rosano C, Galderisi U, Melone MAB, Saturnino C, Peluso G.

Int J Mol Sci. 2020 Oct 8;21(19):7431. doi: 10.3390/ijms21197431.