Artículos por temáticas

Senotherapeutics: Targeting senescent cells for the main age-related diseases

Boccardi V, Mecocci P.

Mech Ageing Dev. 2021 Jul;197:111526. doi: 10.1016/j.mad.2021.111526. Epub 2021 Jun 21.

Inhibition of Histone Deacetylase 6 (HDAC6) as a therapeutic strategy for Alzheimer's disease: A review (2010-2020)

Li Y, Sang S, Ren W, Pei Y, Bian Y, Chen Y, Sun H.

Eur J Med Chem. 2021 Dec 15;226:113874. doi: 10.1016/j.ejmech.2021.113874. Epub 2021 Sep 27.

Nutraceutical and therapeutic potential of Phycocyanobilin for treating Alzheimer's disease

Matamoros BP, Prida JM, Rol GP.

J Biosci. 2021;46:42.

Recent Progress in the Drug Development for the Treatment of Alzheimer's Disease Especially on Inhibition of Amyloid-peptide Aggregation

Liu Y, Cong L, Han C, Li B, Dai R.

Mini Rev Med Chem. 2021;21(8):969-990. doi: 10.2174/1389557520666201127104539.

Inhibition of Astrocytic Histamine N-Methyltransferase as a Possible Target for the Treatment of Alzheimer's Disease

Flores-Clemente C, Nicolás-Vázquez MI, Mera Jiménez E, Hernández-Rodríguez M.

Biomolecules. 2021 Sep 26;11(10):1408. doi: 10.3390/biom11101408.

[Donepezil Reduces Amyloid Precursor Protein Endocytosis by Resulting from Increase in the Expression of Sorting Nexin Protein 33]

Takada-Takatori Y.

Yakugaku Zasshi. 2021;141(6):851-856. doi: 10.1248/yakushi.20-00251-6.

Facilitators, Challenges, and Messaging Strategies for Hispanic/Latino Populations Participating in Alzheimer's Disease and Related Dementias Clinical Research: A Literature Review

Massett HA, Mitchell AK, Alley L, Simoneau E, Burke P, Han SH, Gallop-Goodman G, McGowan M.

J Alzheimers Dis. 2021;82(1):107-127. doi: 10.3233/JAD-201463.

A Comprehensive Analysis into the Therapeutic Application of Natural Products as SIRT6 Modulators in Alzheimer's Disease, Aging, Cancer, Inflammation, and Diabetes

Akter R, Afrose A, Rahman MR, Chowdhury R, Nirzhor SSR, Khan RI, Kabir MT.

Int J Mol Sci. 2021 Apr 17;22(8):4180. doi: 10.3390/ijms22084180.

The Pathogenesis Mechanism, Structure Properties, Potential Drugs and Therapeutic Nanoparticles against the Small Oligomers of Amyloid-β

Wang K, Na L, Duan M.

Curr Top Med Chem. 2021;21(2):151-167. doi: 10.2174/1568026620666200916123000.

The approval of Aduhelm risks eroding public trust in Alzheimer research and the FDA

Karlawish J, Grill JD.

Nat Rev Neurol. 2021 Sep;17(9):523-524. doi: 10.1038/s41582-021-00540-6.

Computer-Based Drug Design of Positive Modulators of Store-Operated Calcium Channels to Prevent Synaptic Dysfunction in Alzheimer's Disease

Hunanyan L, Ghamaryan V, Makichyan A, Popugaeva E.

Int J Mol Sci. 2021 Dec 19;22(24):13618. doi: 10.3390/ijms222413618.

TREM2, microglia, and Alzheimer's disease

Qin Q, Teng Z, Liu C, Li Q, Yin Y, Tang Y.

Mech Ageing Dev. 2021 Apr;195:111438. doi: 10.1016/j.mad.2021.111438. Epub 2021 Jan 28.

Mural Cells: Potential Therapeutic Targets to Bridge Cardiovascular Disease and Neurodegeneration

Lin A, Peiris NJ, Dhaliwal H, Hakim M, Li W, Ganesh S, Ramaswamy Y, Patel S, Misra A.

Cells. 2021 Mar 8;10(3):593. doi: 10.3390/cells10030593.

Mitotherapy: Unraveling a Promising Treatment for Disorders of the Central Nervous System and Other Systemic Conditions

Nascimento-Dos-Santos G, de-Souza-Ferreira E, Linden R, Galina A, Petrs-Silva H.

Cells. 2021 Jul 20;10(7):1827. doi: 10.3390/cells10071827.

An Update on the Routes for the Delivery of Donepezil

Zhao ZQ, Chen BZ, Zhang XP, Zheng H, Guo XD.

Mol Pharm. 2021 Jul 5;18(7):2482-2494. doi: 10.1021/acs.molpharmaceut.1c00290. Epub 2021 Jun 8.