Artículos por temáticas

The efficacy and safety of zolpidem and zopiclone to treat insomnia in Alzheimer's disease: a randomized, triple-blind, placebo-controlled trial

Louzada LL, Machado FV, Quintas JL, Ribeiro GA, Silva MV, Mendonça-Silva DL, Gonçalves BSB, Nóbrega OT, Camargos EF.

Neuropsychopharmacology. 2022 Jan;47(2):570-579. doi: 10.1038/s41386-021-01191-3. Epub 2021 Oct 11.

The role of fatty acid amide hydrolase enzyme inhibitors in Alzheimer's disease

Jain S, Bisht A, Verma K, Negi S, Paliwal S, Sharma S.

Cell Biochem Funct. 2022 Mar;40(2):106-117. doi: 10.1002/cbf.3680. Epub 2021 Dec 21.

Tissue Plasminogen Activator in Central Nervous System Physiology and Pathology: From Synaptic Plasticity to Alzheimer's Disease

Stevenson TK, Moore SJ, Murphy GG, Lawrence DA.

Semin Thromb Hemost. 2022 Apr;48(3):288-300. doi: 10.1055/s-0041-1740265. Epub 2021 Dec 23.

A systematic review and meta-analysis of transcranial direct-current stimulation effects on cognitive function in patients with Alzheimer's disease

Majdi A, van Boekholdt L, Sadigh-Eteghad S, Mc Laughlin M.

Mol Psychiatry. 2022 Apr;27(4):2000-2009. doi: 10.1038/s41380-022-01444-7. Epub 2022 Feb 3.

Pharmacological Exploration of Triazole-based Therapeutics for Alzheimer's Disease: An Overview

Prasanna CAL, Sharma A.

Curr Drug Targets. 2022;23(9):933-953. doi: 10.2174/1389450123666220328153741.

The Molecular Effects of Environmental Enrichment on Alzheimer's Disease

Liew AKY, Teo CH, Soga T.

Mol Neurobiol. 2022 Dec;59(12):7095-7118. doi: 10.1007/s12035-022-03016-w. Epub 2022 Sep 9.

A Narrative Review of the Effects of Citrus Peels and Extracts on Human Brain Health and Metabolism

Matsuzaki K, Nakajima A, Guo Y, Ohizumi Y.

Nutrients. 2022 Apr 28;14(9):1847. doi: 10.3390/nu14091847.

A cultural approach to dementia - insights from US Latino and other minoritized groups

Vila-Castelar C, Fox-Fuller JT, Guzmán-Vélez E, Schoemaker D, Quiroz YT.

Nat Rev Neurol. 2022 May;18(5):307-314. doi: 10.1038/s41582-022-00630-z. Epub 2022 Mar 8.

"Aducanumab" making a comeback in Alzheimer's disease: An old wine in a new bottle

Behl T, Kaur I, Sehgal A, Singh S, Sharma N, Makeen HA, Albratty M, Alhazmi HA, Felemban SG, Alsubayiel AM, Bhatia S, Bungau S.

Biomed Pharmacother. 2022 Apr;148:112746. doi: 10.1016/j.biopha.2022.112746. Epub 2022 Feb 26.

Progress in the development of naturally derived active metabolites-based drugs: Potential therapeutics for Alzheimer's disease

Mani R, Sha Sulthana A, Muthusamy G, Elangovan N.

Biotechnol Appl Biochem. 2022 Dec;69(6):2713-2732. doi: 10.1002/bab.2317. Epub 2022 Feb 8.

Can exercise training teach us how to treat Alzheimer's disease?

Huuha AM, Norevik CS, Moreira JBN, Kobro-Flatmoen A, Scrimgeour N, Kivipelto M, Van Praag H, Ziaei M, Sando SB, Wisløff U, Tari AR.

Ageing Res Rev. 2022 Mar;75:101559. doi: 10.1016/j.arr.2022.101559. Epub 2022 Jan 6.

Targeted Mitochondrial Epigenetics: A New Direction in Alzheimer's Disease Treatment

Song Y, Zhu XY, Zhang XM, Xiong H.

Int J Mol Sci. 2022 Aug 26;23(17):9703. doi: 10.3390/ijms23179703.

Developing a pathway to support the appropriate, affordable, and widespread use of effective Alzheimer's prevention drugs

Reiman EM, Mattke S, Kordower JH, Khachaturian ZS, Khachaturian AS.

Alzheimers Dement. 2022 Jan;18(1):7-9. doi: 10.1002/alz.12533. Epub 2022 Feb 1.

What have we learnt from past failures in Alzheimer's disease drug discovery?

Cacabelos R.

Expert Opin Drug Discov. 2022 Apr;17(4):309-323. doi: 10.1080/17460441.2022.2033724. Epub 2022 Feb 6.

Mechanistic Insights for Drug Repurposing and the Design of Hybrid Drugs for Alzheimer's Disease

Padhi D, Govindaraju T.

J Med Chem. 2022 May 26;65(10):7088-7105. doi: 10.1021/acs.jmedchem.2c00335. Epub 2022 May 13.